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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLK
All Species:
20
Human Site:
T436
Identified Species:
40
UniProt:
Q9H2G2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2G2
NP_055535.2
1235
142695
T436
K
L
E
N
L
P
D
T
E
D
Q
E
T
V
D
Chimpanzee
Pan troglodytes
XP_508017
1236
142782
T437
K
L
E
N
L
P
D
T
E
D
Q
E
T
V
D
Rhesus Macaque
Macaca mulatta
A4K2T0
487
55587
Dog
Lupus familis
XP_544006
1242
143609
T437
R
L
E
N
L
P
D
T
E
D
Q
E
T
V
D
Cat
Felis silvestris
Mouse
Mus musculus
O54988
1233
141438
T434
K
L
E
N
L
P
D
T
Q
D
Q
Q
T
V
D
Rat
Rattus norvegicus
O08815
1206
137870
T436
Q
L
E
S
Q
P
D
T
E
D
Q
Q
T
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518991
740
85845
E115
A
S
Q
L
S
F
E
E
E
K
P
T
E
P
A
Chicken
Gallus gallus
XP_421743
1234
142753
S436
P
I
E
K
N
T
E
S
L
E
E
T
A
E
D
Frog
Xenopus laevis
NP_001079164
950
111798
E325
I
E
E
Q
G
E
A
E
E
E
E
D
S
D
M
Zebra Danio
Brachydanio rerio
Q7ZUQ3
492
56062
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T0S6
669
75091
I44
P
P
E
K
V
F
D
I
M
Y
K
L
G
E
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NB31
497
55620
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
20.2
90.1
N.A.
83.6
78.3
N.A.
33.9
72.1
45.5
20.2
N.A.
22.3
N.A.
20.4
N.A.
Protein Similarity:
100
99.6
29.1
94.6
N.A.
89.8
86.3
N.A.
46.3
81.6
59.7
29.6
N.A.
35.6
N.A.
29.2
N.A.
P-Site Identity:
100
100
0
93.3
N.A.
86.6
73.3
N.A.
6.6
13.3
13.3
0
N.A.
13.3
N.A.
0
N.A.
P-Site Similarity:
100
100
0
100
N.A.
100
93.3
N.A.
20
46.6
40
0
N.A.
26.6
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
9
0
0
0
0
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
50
0
0
42
0
9
0
9
50
% D
% Glu:
0
9
67
0
0
9
17
17
50
17
17
25
9
17
0
% E
% Phe:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
25
0
0
17
0
0
0
0
0
9
9
0
0
0
0
% K
% Leu:
0
42
0
9
34
0
0
0
9
0
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% M
% Asn:
0
0
0
34
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
17
9
0
0
0
42
0
0
0
0
9
0
0
9
0
% P
% Gln:
9
0
9
9
9
0
0
0
9
0
42
17
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
9
0
9
9
0
0
9
0
0
0
0
9
0
0
% S
% Thr:
0
0
0
0
0
9
0
42
0
0
0
17
42
0
0
% T
% Val:
0
0
0
0
9
0
0
0
0
0
0
0
0
42
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _